General review on Cell Therapy
It is proved by the historical documents that animal derived medicines, in a form of powder, decoction, or tincture was successfully used by Asian, American, African and European nations for thousands years.
According to E. W. Berridge a principle similia similibus curantur or “like treats like”, was well known in Europe in the 12th century as a very old, rational, and empiric mode of treatment.
Henry Cornelius Agrippa wrote in the middle of 16th century: “it is well known amongst physicians that brain helps the brain, and lungs, the lungs, etc ...”, “... do animals that are long lived conduce to long life ...”.
Rabbit or Hare, or Sheep and Goat were popular sources for animal origin remedies. In the Natural History, written by Pliny the Elder (AD 23-79) inthe first century AD, it is mentioned: “The ashes of a burnt hare/rabbit, mixed with oil of myrtle, alleviate head-ache”.
“for pains in the kidneys they recommend a hare’s (rabbit’s) kidneys to be swallowed raw, or boiled, but without letting them be touched by the teeth”.
“The kidneys of a hare/rabbit, dried and taken in wine, act as an expellant upon calculi”, etc.
“The membrane in which the kid (of goat) is enclosed in the uterus, dried and taken in wine, acts as an expellant upon the after-birth”.
“For diseases incident to females, a ewe’s placenta is very useful, as already mentioned by us, when speaking of goats”.
After experiments and clinical trials carried out by Dr. Charles-Édouard Brown-Séquard (1817-1894), cellular therapy based on the new manufacturing technology got the second birth at the end of 19th century. It was applicable within mainstream of medicine until beginning of the 20th century. But due to the active and effective application of hormonal remedies, the popularity of cell therapy gradually declined. Nevertheless doctors in Germany, France, Switzerland and Russia continued to use live cells or cell extracts as a part of their daily practice. The leading argument suggested by those doctors was that cell therapy was not limited by the effects of hormones, and it could include substances not yet identified. But science was advancing and now, recent studies have identified peptides that are specific for various organs and can contribute to recovery of the specific organ.
At the picture presented below, results of the SDS-PAGE test [Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis], that demonstrate recognized difference between extracts derived from bovine Liver and Lung [D. I. Maltsev, 2013].
Modern approach in Cell Therapy
Nowadays cell therapy uses the same idea like before: for disease of the lungs, take cells or extracts from the lungs; for disease of the liver use cells or extracts from the liver, etc. To make a conclusion regarding the main location of the problem, doctor should use classic diagnostic protocols of modern medicine, and analyze complaints and symptoms of the patient, blood tests, results of ultrasound and X-ray examination, endoscopic examination, MRI, PET, etc. Patient or client is recommended to undergo blood tests according to his or her age and condition:
• Routine blood test, Lipids, Glucose, Liver and Kidney profile, and Urine test;
• For patients 40 years old and above, it is recommended to check additionally: FSH, LH, DHEA, SHBG, Cortisol, ACTH, Estradiol (total and free), and Progesterone.
• For patients 45 years old and above, it is recommended to check for tumor markers: AFP (Liver ), CEA (various), CA 19-9 (Pancreas, Colorectal area), CA72-4 (Pancreas, Stomach), Cyfra 21-1 (Lungs, etc), CA15-3 (Breast), CA 125 (Ovary).
Aging process & Anti-Aging program
Aging is a natural process of any living being and is a result of various types of limitations of life discovered in the DNA molecule. One of them was called ‘Hayflick limit’ that meant that all cells have limitation in an amount of dividing into two. When this limit is over, the cell will die by apoptosis.
The newer version of limit is described by the shortening telomeres theory, which means, that after each division, the ends of the DNA strands will get shorter and lose the ability to divide. There are also theories based on the accumulation of toxic molecules, or activation of oxidative stress, etc. As a result of the aging process, tissue regeneration is getting slower and activity of the organs declines. Health aging means that the degeneration process is going at the same speed in various organs according to the average standard discovered by the statistical study. Anti-aging programs should support the weakest organs of the body, as well as rejuvenate the body as a whole.
Female Revitalization Combo (7-in-1)
Female Revitalization (FR) combo consists of the most important ingredients that are required to support women's health at the stages before and after menopause. Female Revitalization combo [7-in-1] includes organ specific ingredients: Skin, Brain, Liver, Thymus, Ovary; and general ingredients: Placenta and Foetal Total, the whole body of the rabbit Fetus.
• Skin is the biggest organ of the body; it controls the interaction between internal organs inside and the environment outside; it plays an important role in supporting internal homeostasis. We lose around 70 billion skin cells daily, but skin also regenerates quite fast due to their natural stem cells. Because of the aging process, regeneration of skin becomes slow, and requires additional support.
• Brain is recommended in the case of poor memory, insomnia, difficulty concentrating, lack of focus, emotional instability, hypertension, etc.
Liver helps to balance lipids, glucose, hormones, vitamins, and delay fatty liver; it is recommended for different types of liver diseases, including hepatitis, cirrhosis, gall bladder stones, etc.
• Thymus is one of the major products for immune stimulation. During the early days of life, a baby’s thymus gets a lot of stimuli from viruses, bacteria and parasites. Therefore, thymus is quite active in children and teenagers. As a person ages, his body meets less antigens, hence thymus becomes inactive and reduces it size. As a result, after age 40, a person will experience chronic immunity deficiency. Application of Thymus extracts helps the body to prevent Thymus atrophy and keeps immunity at an effective level.
• Ovary is the most important organ in the anti-aging program of a woman around the ages of 40-60; it is recommended in cases of irregular menstrual cycle, infertility, premature menopause, female frigidity, for anti-aging and revitalization programs, etc.
• Placenta has a general revitalization effect and helps to restore hormonal balance. It is also recommended to treat emaciation, chronic fatigue, anaemia, infertility, female frigidity, premature menopause, etc.
• Foetal Total is one of the most popular products for general revitalization and for an anti-aging program. It includes extracts from all types of cells present in the body.
Additional cell types recommended
Female Revitalization (FR) combo is a universal product (for female), that unite ingredients which are important for the female body. To obtain a healthy condition of the skin, FR combined with the Skin or Mesenchyme may be prescribed. In specific cases, extracts of the specific organs may be added too.
• Ovary – additional application of Ovary is recommended when FSH is higher than the norm; usually it is used before menopause, when the first symptoms of menstrual cycle abnormality start to appear, and for several years after menopause, until all uncomfortable symptoms of menopause are completely gone.
• Heart may be recommended in case of different types of heart diseases, including high blood pressure, high lipids in the blood or intensive physical activity. It should be also added when Homocysteine are found in high levels, even if no traces of heart disease has been diagnosed yet.
• Bone should be added in cases of signs of Osteoporosis, which is commonly found at the age of menopause.
• Placenta may be added additionally, if Uric Acid is lower than middle of normal range.
• Mesenchyme is used for revitalization and immune stimulation. It has ingredients that improves function of Intercellular space, which is the environment which is located between cells. So, in majority cases of chronic diseases, Mesenchyme should be added.
Standard protocols
All products for cellular therapy are not medicines in the modern sense, so prescription should be done individually on the basis of a patient's condition, and not based on the nosological names of diseases. Application of NanoVital products is not therapy in the modern sense, but it is a natural to stimulate or to enhance the body's own reserves. Effects of NanoVital product applications could be recognised by subjective symptoms, or by blood tests, or other tests, if initial abnormalities were detected before. One should use NanoVital products for a duration of at least 2-3 months; the usual protocol includes application of 1-2 vials at least 2-3 times a week.
For a more enhanced anti-aging program, it is recommended to combine FR Combo with NanoVital ‘Skin’ or NanoVital ‘Mesenchyme’.
1. For a woman before menopause: FR Combo (20 vials) + Skin (10 vials)
2. For a woman after menopause: FR Combo (20 vials) + Mesenchyme (10 vials). It is recommended to use 2 vials of FR Combo, and 1 vial of Skin or Mesenchyme, weekly.
If a patient has additional problems, specific products could be added; but in some cases even several combos can be used together, for example,
• patient with diabetes type one can use Female
Revitalization and LPPSIMK;
• patient with digestive problems can use
Female Revitalization and TDSR;
• patient with immune deficiency can use
Female Revitalization and immune;
• patient with osteoporosis can use Female
Revitalization and BCS, etc.
It is recommended not to exceed a dose of 2 vials of various NanoVital products daily, and 6 - 8 vials weekly.
It is proved by the historical documents that animal derived medicines, in a form of powder, decoction, or tincture was successfully used by Asian, American, African and European nations for thousands years.
According to E. W. Berridge a principle similia similibus curantur or “like treats like”, was well known in Europe in the 12th century as a very old, rational, and empiric mode of treatment.
Henry Cornelius Agrippa wrote in the middle of 16th century: “it is well known amongst physicians that brain helps the brain, and lungs, the lungs, etc ...”, “... do animals that are long lived conduce to long life ...”.
Rabbit or Hare, or Sheep and Goat were popular sources for animal origin remedies. In the Natural History, written by Pliny the Elder (AD 23-79) inthe first century AD, it is mentioned: “The ashes of a burnt hare/rabbit, mixed with oil of myrtle, alleviate head-ache”.
“for pains in the kidneys they recommend a hare’s (rabbit’s) kidneys to be swallowed raw, or boiled, but without letting them be touched by the teeth”.
“The kidneys of a hare/rabbit, dried and taken in wine, act as an expellant upon calculi”, etc.
“The membrane in which the kid (of goat) is enclosed in the uterus, dried and taken in wine, acts as an expellant upon the after-birth”.
“For diseases incident to females, a ewe’s placenta is very useful, as already mentioned by us, when speaking of goats”.
After experiments and clinical trials carried out by Dr. Charles-Édouard Brown-Séquard (1817-1894), cellular therapy based on the new manufacturing technology got the second birth at the end of 19th century. It was applicable within mainstream of medicine until beginning of the 20th century. But due to the active and effective application of hormonal remedies, the popularity of cell therapy gradually declined. Nevertheless doctors in Germany, France, Switzerland and Russia continued to use live cells or cell extracts as a part of their daily practice. The leading argument suggested by those doctors was that cell therapy was not limited by the effects of hormones, and it could include substances not yet identified. But science was advancing and now, recent studies have identified peptides that are specific for various organs and can contribute to recovery of the specific organ.
At the picture presented below, results of the SDS-PAGE test [Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis], that demonstrate recognized difference between extracts derived from bovine Liver and Lung [D. I. Maltsev, 2013].
Modern approach in Cell Therapy
Nowadays cell therapy uses the same idea like before: for disease of the lungs, take cells or extracts from the lungs; for disease of the liver use cells or extracts from the liver, etc. To make a conclusion regarding the main location of the problem, doctor should use classic diagnostic protocols of modern medicine, and analyze complaints and symptoms of the patient, blood tests, results of ultrasound and X-ray examination, endoscopic examination, MRI, PET, etc. Patient or client is recommended to undergo blood tests according to his or her age and condition:
• Routine blood test, Lipids, Glucose, Liver and Kidney profile, and Urine test;
• For patients 40 years old and above, it is recommended to check additionally: FSH, LH, DHEA, SHBG, Cortisol, ACTH, Estradiol (total and free), and Progesterone.
• For patients 45 years old and above, it is recommended to check for tumor markers: AFP (Liver ), CEA (various), CA 19-9 (Pancreas, Colorectal area), CA72-4 (Pancreas, Stomach), Cyfra 21-1 (Lungs, etc), CA15-3 (Breast), CA 125 (Ovary).
Aging process & Anti-Aging program
Aging is a natural process of any living being and is a result of various types of limitations of life discovered in the DNA molecule. One of them was called ‘Hayflick limit’ that meant that all cells have limitation in an amount of dividing into two. When this limit is over, the cell will die by apoptosis.
The newer version of limit is described by the shortening telomeres theory, which means, that after each division, the ends of the DNA strands will get shorter and lose the ability to divide. There are also theories based on the accumulation of toxic molecules, or activation of oxidative stress, etc. As a result of the aging process, tissue regeneration is getting slower and activity of the organs declines. Health aging means that the degeneration process is going at the same speed in various organs according to the average standard discovered by the statistical study. Anti-aging programs should support the weakest organs of the body, as well as rejuvenate the body as a whole.
Female Revitalization Combo (7-in-1)
Female Revitalization (FR) combo consists of the most important ingredients that are required to support women's health at the stages before and after menopause. Female Revitalization combo [7-in-1] includes organ specific ingredients: Skin, Brain, Liver, Thymus, Ovary; and general ingredients: Placenta and Foetal Total, the whole body of the rabbit Fetus.
• Skin is the biggest organ of the body; it controls the interaction between internal organs inside and the environment outside; it plays an important role in supporting internal homeostasis. We lose around 70 billion skin cells daily, but skin also regenerates quite fast due to their natural stem cells. Because of the aging process, regeneration of skin becomes slow, and requires additional support.
• Brain is recommended in the case of poor memory, insomnia, difficulty concentrating, lack of focus, emotional instability, hypertension, etc.
Liver helps to balance lipids, glucose, hormones, vitamins, and delay fatty liver; it is recommended for different types of liver diseases, including hepatitis, cirrhosis, gall bladder stones, etc.
• Thymus is one of the major products for immune stimulation. During the early days of life, a baby’s thymus gets a lot of stimuli from viruses, bacteria and parasites. Therefore, thymus is quite active in children and teenagers. As a person ages, his body meets less antigens, hence thymus becomes inactive and reduces it size. As a result, after age 40, a person will experience chronic immunity deficiency. Application of Thymus extracts helps the body to prevent Thymus atrophy and keeps immunity at an effective level.
• Ovary is the most important organ in the anti-aging program of a woman around the ages of 40-60; it is recommended in cases of irregular menstrual cycle, infertility, premature menopause, female frigidity, for anti-aging and revitalization programs, etc.
• Placenta has a general revitalization effect and helps to restore hormonal balance. It is also recommended to treat emaciation, chronic fatigue, anaemia, infertility, female frigidity, premature menopause, etc.
• Foetal Total is one of the most popular products for general revitalization and for an anti-aging program. It includes extracts from all types of cells present in the body.
Additional cell types recommended
Female Revitalization (FR) combo is a universal product (for female), that unite ingredients which are important for the female body. To obtain a healthy condition of the skin, FR combined with the Skin or Mesenchyme may be prescribed. In specific cases, extracts of the specific organs may be added too.
• Ovary – additional application of Ovary is recommended when FSH is higher than the norm; usually it is used before menopause, when the first symptoms of menstrual cycle abnormality start to appear, and for several years after menopause, until all uncomfortable symptoms of menopause are completely gone.
• Heart may be recommended in case of different types of heart diseases, including high blood pressure, high lipids in the blood or intensive physical activity. It should be also added when Homocysteine are found in high levels, even if no traces of heart disease has been diagnosed yet.
• Bone should be added in cases of signs of Osteoporosis, which is commonly found at the age of menopause.
• Placenta may be added additionally, if Uric Acid is lower than middle of normal range.
• Mesenchyme is used for revitalization and immune stimulation. It has ingredients that improves function of Intercellular space, which is the environment which is located between cells. So, in majority cases of chronic diseases, Mesenchyme should be added.
Standard protocols
All products for cellular therapy are not medicines in the modern sense, so prescription should be done individually on the basis of a patient's condition, and not based on the nosological names of diseases. Application of NanoVital products is not therapy in the modern sense, but it is a natural to stimulate or to enhance the body's own reserves. Effects of NanoVital product applications could be recognised by subjective symptoms, or by blood tests, or other tests, if initial abnormalities were detected before. One should use NanoVital products for a duration of at least 2-3 months; the usual protocol includes application of 1-2 vials at least 2-3 times a week.
For a more enhanced anti-aging program, it is recommended to combine FR Combo with NanoVital ‘Skin’ or NanoVital ‘Mesenchyme’.
1. For a woman before menopause: FR Combo (20 vials) + Skin (10 vials)
2. For a woman after menopause: FR Combo (20 vials) + Mesenchyme (10 vials). It is recommended to use 2 vials of FR Combo, and 1 vial of Skin or Mesenchyme, weekly.
If a patient has additional problems, specific products could be added; but in some cases even several combos can be used together, for example,
• patient with diabetes type one can use Female
Revitalization and LPPSIMK;
• patient with digestive problems can use
Female Revitalization and TDSR;
• patient with immune deficiency can use
Female Revitalization and immune;
• patient with osteoporosis can use Female
Revitalization and BCS, etc.
It is recommended not to exceed a dose of 2 vials of various NanoVital products daily, and 6 - 8 vials weekly.
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